Is alpha-lipoic acid better than vitamin C?

Is alpha-lipoic acid better than vitamin C?

A relatively unknown antioxidant, alpha-lipoic acid, may be more potent than vitamins C and E.

How is alpha-lipoic acid best absorbed?

Studies show that about 30% to 40% of the oral dose of an ALA supplement is absorbed. ALA may be better absorbed if it is taken on an empty stomach.

How much alpha-lipoic acid should you take a day?

Because alpha-lipoic acid is an unproven treatment, there is no established dose. However, studies have used between 600-1,800 milligrams daily for diabetes and neuropathy; one review concluded that the evidence is convincing for the use of 600 milligrams daily for three weeks on symptoms of diabetic neuropathy.

Can I take alpha-lipoic acid every day?

BY MOUTH: For nerve pain in people with diabetes (diabetic neuropathy): 600-1800 mg of alpha-lipoic acid per day. For high levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia): 300-1200 mg of alpha-lipoic acid per day for up to 16 weeks.

How long does it take for alpha-lipoic acid to work?

Possibly Effective for Taking 600-1800 mg of alpha-lipoic acid by mouth or by IV seems to improve symptoms such as burning, pain, and numbness in the legs and arms of people with diabetes. It may take 3 to 5 weeks of treatment for symptoms to improve.

What is the best time of day to take alpha-lipoic acid?

Alpha-lipoic supplements are best taken on an empty stomach, as certain foods can lower the acid's bioavailability (40). Though there is no set dosage, most evidence suggests that 300–600 mg is sufficient and safe. Alternatively, you can follow the instructions on the back of the bottle.

Are there any drug interactions with alpha lipoic acid?

Possible Drug Interactions. Alpha lipoic acid can combine with these drugs to further reduce blood sugar levels, resulting in hypoglycemia (low blood sugar). Tell your doctor before taking alpha lipoic acid, and monitor your blood sugar levels closely; your doctor may need to adjust your medication doses.

Is it safe to take alpha lipoic acid supplements?

Alpha lipoic acid also contains sulfhydryl molecules, and some researchers speculated that the amounts of alpha lipoic acid found in supplements (much higher than that found in food) could also trigger IAS.

Do you need to take thiamine with alpha lipoic acid?

Others indicate that the alpha lipoic acid dosage involved in this study was very high. They suggest that patients susceptible to thiamine deficiency and taking high doses of alpha lipoic acid may need to take a thiamine supplement to counteract this potential effect.

How does lipoic acid affect vitamin C and E?

Lipoic acid has been shown to extend the activity of vitamins C and E, also raising ubiquinol and intracellular glutathione. [xxiii], [xxiv] Mechanistically, lipoic acid has been shown to impact endothelial and mitochondrial function – factors which also may play into many of these conditions.